Mir Wais Yasini is the son of Maulvi Abdul Sattar.
He was born in 1963 in Tahir village of Kama district of Nangarhar province.
He migrated to Pakistan after the invasion of Russian troops and got admission in the Islamabad International University.
He got his master degree in Sharia and Political Science from the same university.
He joined the Afghan Red Crescent Society as its head in Nangarhar in 2002 and then worked as director of foreign relations and economic affairs with the Ministry of Finance.
He was member of the Emergency Loya Jirga convened in 2002 and then served as deputy of the Loya Jirga, director of counter narcotics and deputy minister counter narcotics.
He made his way to the Wolesi Jirga as a result of the 2005 parliamentary elections and appointed as first deputy of the Wolesi Jirga after some time.
He can speak Pashto, Dari, Arabic, English and Urdu languages.